Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system

mGlu5 receptors are involved in mechanisms of activity-dependent synaptic plasticity, and are targeted by drugs developed for the treatment of CNS disorders. We report that mGlu3 receptors, which are traditionally linked to the control of neurotransmitter release, support mGlu5 receptor signaling in...

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Pubblicato in:Neuropharmacology
Autori principali: Menna, Luisa Di, Joffe, Max E., Iacovelli, Luisa, Orlando, Rosamaria, Lindsley, Craig W., Mairesse, Jèrome, Gressèns, Pierre, Cannella, Milena, Caraci, Filippo, Copani, Agata, Bruno, Valeria, Battaglia, Giuseppe, Conn, P. Jeffrey, Nicoletti, Ferdinando
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263139/
https://ncbi.nlm.nih.gov/pubmed/29079293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.10.026
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