mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists

Group II metabotropic glutamate receptors (mGluRs) couple to the inhibitory G-protein Gi. The group II mGluRs include two subtypes, mGlu2 and mGlu3, and their pharmacological activation produces analgesic effects in inflammatory and neuropathic pain states. However, the specific contribution of each...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zammataro, Magda, Chiechio, Santina, Montana, Michael C, Traficante, Anna, Copani, Agata, Nicoletti, Ferdinando, Gereau, Robert W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Short Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030510/
https://ncbi.nlm.nih.gov/pubmed/21235748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-6
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