The Use of Knock-Out Mice Unravels Distinct Roles for mGlu2 and mGlu3 Metabotropic Glutamate Receptors in Mechanisms of Neurodegeneration/Neuroprotection

Dual metabotropic glutamate 2/3 (mGlu2/3) receptor agonists have been examined with success in the clinic with positive proof of efficacy in several tests of anxiety and schizophrenia. Moreover, a large body of evidence has accumulated that these drugs have significant neuroprotective potential. An...

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Foilsithe in:J Neurosci
Main Authors: Corti, Corrado, Battaglia, Giuseppe, Molinaro, Gemma, Riozzi, Barbara, Pittaluga, Anna, Corsi, Mauro, Mugnaini, Manolo, Nicoletti, Ferdinando, Bruno, Valeria
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2007
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673047/
https://ncbi.nlm.nih.gov/pubmed/17670976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1889-07.2007
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