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Single-molecule long-read sequencing reveals the chromatin basis of gene expression
Genome-wide chromatin accessibility and nucleosome occupancy profiles have been widely investigated, while the long-range dynamics remain poorly studied at the single-cell level. Here, we present a new experimental approach, methyltransferase treatment followed by single-molecule long-read sequencin...
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| 出版年: | Genome Res |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673713/ https://ncbi.nlm.nih.gov/pubmed/31201211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.251116.119 |
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