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Performance difference of graph-based and alignment-based hybrid error correction methods for error-prone long reads

The error-prone third-generation sequencing (TGS) long reads can be corrected by the high-quality second-generation sequencing (SGS) short reads, which is referred to as hybrid error correction. We here investigate the influences of the principal algorithmic factors of two major types of hybrid erro...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Wang, Anqi, Au, Kin Fai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966875/
https://ncbi.nlm.nih.gov/pubmed/31952552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1885-y
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