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Improving PacBio Long Read Accuracy by Short Read Alignment
The recent development of third generation sequencing (TGS) generates much longer reads than second generation sequencing (SGS) and thus provides a chance to solve problems that are difficult to study through SGS alone. However, higher raw read error rates are an intrinsic drawback in most TGS techn...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464235/ https://ncbi.nlm.nih.gov/pubmed/23056399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046679 |
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