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Improving PacBio Long Read Accuracy by Short Read Alignment

The recent development of third generation sequencing (TGS) generates much longer reads than second generation sequencing (SGS) and thus provides a chance to solve problems that are difficult to study through SGS alone. However, higher raw read error rates are an intrinsic drawback in most TGS techn...

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Dettagli Bibliografici
Autori principali: Au, Kin Fai, Underwood, Jason G., Lee, Lawrence, Wong, Wing Hung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464235/
https://ncbi.nlm.nih.gov/pubmed/23056399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046679
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