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Performance difference of graph-based and alignment-based hybrid error correction methods for error-prone long reads

The error-prone third-generation sequencing (TGS) long reads can be corrected by the high-quality second-generation sequencing (SGS) short reads, which is referred to as hybrid error correction. We here investigate the influences of the principal algorithmic factors of two major types of hybrid erro...

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Veröffentlicht in:Genome Biol
Hauptverfasser: Wang, Anqi, Au, Kin Fai
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966875/
https://ncbi.nlm.nih.gov/pubmed/31952552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1885-y
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