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A Statistical Method for Observing Personal Diploid Methylomes and Transcriptomes with Single-Molecule Real-Time Sequencing

We address the problem of observing personal diploid methylomes, CpG methylome pairs of homologous chromosomes that are distinguishable with respect to phased heterozygous variants (PHVs), which is challenging due to scarcity of PHVs in personal genomes. Single molecule real-time (SMRT) sequencing i...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Suzuki, Yuta, Wang, Yunhao, Au, Kin Fai, Morishita, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162384/
https://ncbi.nlm.nih.gov/pubmed/30235838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9090460
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