Phased Diploid Genome Assembly with Single Molecule Real-Time Sequencing

While genome assembly projects have been successful in a number of haploid or inbred species, one of the main current challenges is assembling non-inbred or rearranged heterozygous genomes. To address this critical need, we introduce the open-source FALCON and FALCON-Unzip algorithms (https://github...

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Publicado no:Nat Methods
Main Authors: Chin, Chen-Shan, Peluso, Paul, Sedlazeck, Fritz J., Nattestad, Maria, Concepcion, Gregory T., Clum, Alicia, Dunn, Christopher, O’Malley, Ronan, Figueroa-Balderas, Rosa, Morales-Cruz, Abraham, Cramer, Grant R., Delledonne, Massimo, Luo, Chongyuan, Ecker, Joseph R., Cantu, Dario, Rank, David R., Schatz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503144/
https://ncbi.nlm.nih.gov/pubmed/27749838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4035
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