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A Statistical Method for Observing Personal Diploid Methylomes and Transcriptomes with Single-Molecule Real-Time Sequencing

We address the problem of observing personal diploid methylomes, CpG methylome pairs of homologous chromosomes that are distinguishable with respect to phased heterozygous variants (PHVs), which is challenging due to scarcity of PHVs in personal genomes. Single molecule real-time (SMRT) sequencing i...

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Bibliografische gegevens
Gepubliceerd in:Genes (Basel)
Hoofdauteurs: Suzuki, Yuta, Wang, Yunhao, Au, Kin Fai, Morishita, Shinichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162384/
https://ncbi.nlm.nih.gov/pubmed/30235838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9090460
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