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A Statistical Method for Observing Personal Diploid Methylomes and Transcriptomes with Single-Molecule Real-Time Sequencing

We address the problem of observing personal diploid methylomes, CpG methylome pairs of homologous chromosomes that are distinguishable with respect to phased heterozygous variants (PHVs), which is challenging due to scarcity of PHVs in personal genomes. Single molecule real-time (SMRT) sequencing i...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Suzuki, Yuta, Wang, Yunhao, Au, Kin Fai, Morishita, Shinichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162384/
https://ncbi.nlm.nih.gov/pubmed/30235838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9090460
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