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The Inhalation Anesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Amyloid β-Protein Accumulation

The anesthetic isoflurane has been reported to induce apoptosis and increase Aβ generation and aggregation. However, the molecular mechanism underlying these effects remains unknown. We therefore set out to assess whether the effects of isoflurane on apoptosis are linked to amyloid β-protein (Aβ) ge...

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Vydáno v:J Neurosci
Hlavní autoři: Xie, Zhongcong, Dong, Yuanlin, Maeda, Uta, Moir, Robert D., Xia, Weiming, Culley, Deborah J., Crosby, Gregory, Tanzi, Rudolph E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673586/
https://ncbi.nlm.nih.gov/pubmed/17287498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5320-06.2007
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