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The Inhalation Anesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Amyloid β-Protein Accumulation

The anesthetic isoflurane has been reported to induce apoptosis and increase Aβ generation and aggregation. However, the molecular mechanism underlying these effects remains unknown. We therefore set out to assess whether the effects of isoflurane on apoptosis are linked to amyloid β-protein (Aβ) ge...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Xie, Zhongcong, Dong, Yuanlin, Maeda, Uta, Moir, Robert D., Xia, Weiming, Culley, Deborah J., Crosby, Gregory, Tanzi, Rudolph E.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673586/
https://ncbi.nlm.nih.gov/pubmed/17287498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5320-06.2007
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