The inhalation anesthetic isoflurane increases levels of proinflammatory cytokine TNF-α, IL-6 and IL-1β

Anesthetics have been reported to promote Alzheimer’s disease (AD) neuropathogenesis by inducing β-amyloid protein accumulation and apoptosis. Neuroinflammation is associated with the emergence of AD. We therefore set out to determine the effects of the common anesthetic isoflurane on the levels of...

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Autori principali: Wu, Xu, Lu, Yan, Dong, Yuanlin, Zhang, Guohua, Zhang, Yiying, Xu, Zhipeng, Culley, Deborah J., Crosby, Gregory, Marcantonio, Edward R., Tanzi, Rudolph E., Xie, Zhongcong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117127/
https://ncbi.nlm.nih.gov/pubmed/21190757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.11.002
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