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The Inhalation Anesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Amyloid β-Protein Accumulation

The anesthetic isoflurane has been reported to induce apoptosis and increase Aβ generation and aggregation. However, the molecular mechanism underlying these effects remains unknown. We therefore set out to assess whether the effects of isoflurane on apoptosis are linked to amyloid β-protein (Aβ) ge...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Xie, Zhongcong, Dong, Yuanlin, Maeda, Uta, Moir, Robert D., Xia, Weiming, Culley, Deborah J., Crosby, Gregory, Tanzi, Rudolph E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673586/
https://ncbi.nlm.nih.gov/pubmed/17287498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5320-06.2007
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