Anesthetics Isoflurane and Desflurane Differently Affect Mitochondrial Function, Learning, and Memory

OBJECTIVE: There are approximately 8.5 million Alzheimer disease (AD) patients who need anesthesia and surgery care every year. The inhalation anesthetic isoflurane, but not desflurane, has been shown to induce caspase activation and apoptosis, which are part of AD neuropathogenesis, through the mit...

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Main Authors: Zhang, Yiying, Xu, Zhipeng, Wang, Hui, Dong, Yuanlin, Shi, Hai Ning, Culley, Deborah J., Crosby, Gregory, Marcantonio, Edward R., Tanzi, Rudolph E., Xie, Zhongcong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942786/
https://ncbi.nlm.nih.gov/pubmed/22368036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23536
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