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Anesthetics Isoflurane and Desflurane Differently Affect Mitochondrial Function, Learning, and Memory

OBJECTIVE: There are approximately 8.5 million Alzheimer disease (AD) patients who need anesthesia and surgery care every year. The inhalation anesthetic isoflurane, but not desflurane, has been shown to induce caspase activation and apoptosis, which are part of AD neuropathogenesis, through the mit...

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Autori principali: Zhang, Yiying, Xu, Zhipeng, Wang, Hui, Dong, Yuanlin, Shi, Hai Ning, Culley, Deborah J., Crosby, Gregory, Marcantonio, Edward R., Tanzi, Rudolph E., Xie, Zhongcong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942786/
https://ncbi.nlm.nih.gov/pubmed/22368036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23536
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