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The Common Inhalational Anesthetic Sevoflurane Induces Apoptosis and Increases β-Amyloid Protein Levels

OBJECTIVE: To assess the effects of sevoflurane, the most commonly used inhalation anesthetic, on apoptosis and β-amyloid protein (Aβ) levels in vitro and in vivo. SUBJECTS: Naive mice, H4 human neuroglioma cells, and H4 human neuroglioma cells stably transfected to express full-length amyloid precu...

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Detalhes bibliográficos
Main Authors: Dong, Yuanlin, Zhang, Guohua, Zhang, Bin, Moir, Robert D., Xia, Weiming, Marcantonio, Edward R., Culley, Deborah J., Crosby, Gregory, Tanzi, Rudolph E., Xie, Zhongcong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748878/
https://ncbi.nlm.nih.gov/pubmed/19433662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.48
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