The Membrane Attack Complex of the Complement System Is Essential for Rapid Wallerian Degeneration

The complement (C) system plays an important role in myelin breakdown during Wallerian degeneration (WD). The pathway and mechanism involved are, however, not clear. In a crush injury model of the sciatic nerve, we show that C6, necessary for the assembly of the membrane attack complex (MAC), is ess...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ramaglia, Valeria, King, Rosalind Helen Mary, Nourallah, Michelle, Wolterman, Ruud, de Jonge, Rosalein, Ramkema, Marja, Vigar, Miriam Ann, van der Wetering, Sandra, Morgan, Brian Paul, Troost, Dirk, Baas, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672891/
https://ncbi.nlm.nih.gov/pubmed/17634361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5623-06.2007
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