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Complement activation at the motor end-plates in amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease with no available therapy. Components of the innate immune system are activated in the spinal cord and central nervous system of ALS patients. Studies in the SOD1(G93A) mouse show deposition of C1q and C...

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Publicat a:J Neuroinflammation
Autors principals: Bahia El Idrissi, Nawal, Bosch, Sanne, Ramaglia, Valeria, Aronica, Eleonora, Baas, Frank, Troost, Dirk
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823861/
https://ncbi.nlm.nih.gov/pubmed/27056040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0538-2
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