Transient Overexpression of Striatal D(2) Receptors Impairs Operant Motivation and Interval Timing

The striatum receives prominent dopaminergic innervation that is integral to appetitive learning, performance, and motivation. Signaling through the dopamine D(2) receptor is critical for all of these processes. For instance, drugs with high affinity for the D(2) receptor potently alter timing of op...

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Vydáno v:J Neurosci
Hlavní autoři: Drew, Michael R., Simpson, Eleanor H., Kellendonk, Christoph, Herzberg, William G., Lipatova, Olga, Fairhurst, Stephen, Kandel, Eric R., Malapani, Chara, Balsam, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672869/
https://ncbi.nlm.nih.gov/pubmed/17634367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1736-07.2007
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