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Impaired Timing Precision Produced by Striatal D2 Receptor Overexpression is Mediated by Cognitive and Motivational Deficits

Increased striatal dopamine D2 receptor activity is thought to contribute to the pathophysiology of schizophrenia. To model this condition in mice, Kellendonk et al. (2006) generated transgenic mice which selectively overexpress the D2 receptor in striatum (D2OE). Drew et al. (2007) reported that D2...

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Detalles Bibliográficos
Main Authors: Ward, Ryan D., Kellendonk, Christoph, Simpson, Eleanor H., Lipatova, Olga, Drew, Michael R., Fairhurst, Stephen, Kandel, Eric R., Balsam, Peter D
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791672/
https://ncbi.nlm.nih.gov/pubmed/19634929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/a0016503
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