Transient Overexpression of Striatal D(2) Receptors Impairs Operant Motivation and Interval Timing

The striatum receives prominent dopaminergic innervation that is integral to appetitive learning, performance, and motivation. Signaling through the dopamine D(2) receptor is critical for all of these processes. For instance, drugs with high affinity for the D(2) receptor potently alter timing of op...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Drew, Michael R., Simpson, Eleanor H., Kellendonk, Christoph, Herzberg, William G., Lipatova, Olga, Fairhurst, Stephen, Kandel, Eric R., Malapani, Chara, Balsam, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672869/
https://ncbi.nlm.nih.gov/pubmed/17634367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1736-07.2007
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