Pharmacologic Rescue of Motivational Deficit in an Animal Model of the Negative Symptoms of Schizophrenia

BACKGROUND: Deficits in incentive motivation, the energizing of behavior in pursuit of a goal, occur in many psychiatric disorders including schizophrenia. We previously reported deficits in both cognition and incentive motivation in a transgenic mouse model of increased striatal-specific dopamine D...

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Hoofdauteurs: Simpson, Eleanor H., Kellendonk, Christoph, Ward, Ryan D., Richards, Vanessa, Lipatova, Olga, Fairhurst, Stephen, Kandel, Eric R., Balsam, Peter D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170714/
https://ncbi.nlm.nih.gov/pubmed/21414604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.01.012
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