Dissociation of Hedonic Reaction to Reward and Incentive Motivation in an Animal Model of the Negative Symptoms of Schizophrenia

We previously showed that mice that selectively and reversibly overexpress striatal D2 receptors (D2R-OE) model the negative symptoms of schizophrenia. Specifically, D2R-OE mice display a deficit in incentive motivation. The present studies investigated the basis for this deficit. First, we assessed...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ward, Ryan D, Simpson, Eleanor H, Richards, Vanessa L, Deo, Gita, Taylor, Kathleen, Glendinning, John I, Kandel, Eric R, Balsam, Peter D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358738/
https://ncbi.nlm.nih.gov/pubmed/22414818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados