Dissociation of Hedonic Reaction to Reward and Incentive Motivation in an Animal Model of the Negative Symptoms of Schizophrenia

We previously showed that mice that selectively and reversibly overexpress striatal D2 receptors (D2R-OE) model the negative symptoms of schizophrenia. Specifically, D2R-OE mice display a deficit in incentive motivation. The present studies investigated the basis for this deficit. First, we assessed...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ward, Ryan D, Simpson, Eleanor H, Richards, Vanessa L, Deo, Gita, Taylor, Kathleen, Glendinning, John I, Kandel, Eric R, Balsam, Peter D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358738/
https://ncbi.nlm.nih.gov/pubmed/22414818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.15
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia