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Progressive Motor Neuronopathy: A Critical Role of the Tubulin Chaperone TBCE in Axonal Tubulin Routing from the Golgi Apparatus

Axonal degeneration represents one of the earliest pathological features in motor neuron diseases. We here studied the underlying molecular mechanisms in progressive motor neuronopathy (pmn) mice mutated in the tubulin-specific chaperone TBCE. We demonstrate that TBCE is a peripheral membrane-associ...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Schaefer, Michael K. E., Schmalbruch, Henning, Buhler, Emmanuelle, Lopez, Catherine, Martin, Natalia, Guénet, Jean-Louis, Haase, Georg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672183/
https://ncbi.nlm.nih.gov/pubmed/17699660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1599-07.2007
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