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Colchicine Blocks Tubulin Heterodimer Recycling by Tubulin Cofactors TBCA, TBCB, and TBCE

Colchicine has been used to treat gout and, more recently, to effectively prevent autoinflammatory diseases and both primary and recurrent episodes of pericarditis. The anti-inflammatory action of colchicine seems to result from irreversible inhibition of tubulin polymerization and microtubule (MT)...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Nolasco, Sofia, Bellido, Javier, Serna, Marina, Carmona, Bruno, Soares, Helena, Zabala, Juan Carlos
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100514/
https://ncbi.nlm.nih.gov/pubmed/33968934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.656273
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