Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease

Progressive motor neuronopathy (pmn) mutant mice have been widely used as a model for human motoneuron disease. Mice that are homozygous for the pmn gene defect appear healthy at birth but develop progressive motoneuron disease, resulting in severe skeletal muscle weakness and respiratory failure by...

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Detalhes bibliográficos
Main Authors: Bömmel, Heike, Xie, Gang, Rossoll, Wilfried, Wiese, Stefan, Jablonka, Sibylle, Boehm, Thomas, Sendtner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173089/
https://ncbi.nlm.nih.gov/pubmed/12446740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208001
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