Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease

Progressive motor neuronopathy (pmn) mutant mice have been widely used as a model for human motoneuron disease. Mice that are homozygous for the pmn gene defect appear healthy at birth but develop progressive motoneuron disease, resulting in severe skeletal muscle weakness and respiratory failure by...

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Autores principales: Bömmel, Heike, Xie, Gang, Rossoll, Wilfried, Wiese, Stefan, Jablonka, Sibylle, Boehm, Thomas, Sendtner, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173089/
https://ncbi.nlm.nih.gov/pubmed/12446740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200208001
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