Progressive Motor Neuronopathy: A Critical Role of the Tubulin Chaperone TBCE in Axonal Tubulin Routing from the Golgi Apparatus

Axonal degeneration represents one of the earliest pathological features in motor neuron diseases. We here studied the underlying molecular mechanisms in progressive motor neuronopathy (pmn) mice mutated in the tubulin-specific chaperone TBCE. We demonstrate that TBCE is a peripheral membrane-associ...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Schaefer, Michael K. E., Schmalbruch, Henning, Buhler, Emmanuelle, Lopez, Catherine, Martin, Natalia, Guénet, Jean-Louis, Haase, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672183/
https://ncbi.nlm.nih.gov/pubmed/17699660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1599-07.2007
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