Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3

Fetal hematopoietic stem and progenitor cells (HSPCs) hold promise to cure a wide array of hematological diseases, and we previously found a role for the RNA-binding protein (RBP) Lin28b in respecifying adult HSPCs to resemble their fetal counterparts. Here we show by single-cell RNA sequencing that...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Wang, Saifeng, Chim, Bryan, Su, Yijun, Khil, Pavel, Wong, Madeline, Wang, Xiantao, Foroushani, Amir, Smith, Patrick T., Liu, Xiuhuai, Li, Rui, Ganesan, Sundar, Kanellopoulou, Chrysi, Hafner, Markus, Muljo, Stefan A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672051/
https://ncbi.nlm.nih.gov/pubmed/31221665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.325100.119
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