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Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis

The immune system develops in waves during ontogeny, being initially populated by cells generated from fetal hematopoietic stem cells (HSCs) and later by cells derived from adult HSCs. Remarkably, the genetic programs that control these two distinct stem cell fates remain poorly understood. We repor...

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Autors principals: Yuan, Joan, Nguyen, Cuong K., Liu, Xiuhuai, Kanellopoulou, Chrysi, Muljo, Stefan A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471381/
https://ncbi.nlm.nih.gov/pubmed/22345399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1216557
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