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Lin28 enhances tissue repair by reprogramming cellular metabolism

Regeneration capacity declines with age, but why juvenile organisms show enhanced tissue repair remains unexplained. Lin28a, a highly-conserved RNA binding protein expressed during embryogenesis, plays roles in development, pluripotency and metabolism. To determine if Lin28a might influence tissue r...

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Detalhes bibliográficos
Main Authors: Shyh-Chang, Ng, Zhu, Hao, de Soysa, T. Yvanka, Shinoda, Gen, Seligson, Marc T., Tsanov, Kaloyan M., Nguyen, Liem, Asara, John M., Cantley, Lewis C., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917449/
https://ncbi.nlm.nih.gov/pubmed/24209617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.059
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