Fetal deficiency of Lin28 programs life-long aberrations in growth and glucose metabolism

LIN28A/B are RNA binding proteins implicated by genetic association studies in human growth and glucose metabolism. Mice with ectopic over-expression of Lin28a have shown related phenotypes. Here we describe the first comprehensive analysis of the physiologic consequences of Lin28a and Lin28b defici...

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Detalhes bibliográficos
Main Authors: Shinoda, Gen, Shyh-Chang, Ng, de Soysa, T. Yvanka, Zhu, Hao, Seligson, Marc T., Shah, Samar P., Abo-Sido, Nora, Yabuuchi, Akiko, Hagan, John P., Gregory, Richard I., Asara, John M., Cantley, Lewis C., Moss, Eric G., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775935/
https://ncbi.nlm.nih.gov/pubmed/23666760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1423
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