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Lin28: Primal Regulator of Growth and Metabolism in Stem Cells
In recent years, the highly conserved Lin28 RNA-binding proteins have emerged as factors that define stemness in several tissue lineages. Lin28 proteins repress let-7 microRNAs and influence mRNA translation, thereby regulating the self-renewal of mammalian embryonic stem cells. Subsequent discoveri...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652335/ https://ncbi.nlm.nih.gov/pubmed/23561442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.03.005 |
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