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Lin28: Primal Regulator of Growth and Metabolism in Stem Cells

In recent years, the highly conserved Lin28 RNA-binding proteins have emerged as factors that define stemness in several tissue lineages. Lin28 proteins repress let-7 microRNAs and influence mRNA translation, thereby regulating the self-renewal of mammalian embryonic stem cells. Subsequent discoveri...

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Bibliographic Details
Main Authors: Shyh-Chang, Ng, Daley, George Q.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652335/
https://ncbi.nlm.nih.gov/pubmed/23561442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.03.005
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