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FOXH1 Is Regulated by NANOG and LIN28 for Early-stage Reprogramming

FOXH1 is a primitive-streak specifier and ACTIVIN co-effector that plays an important role in development, and positively regulates the generation of human induced pluripotent stem cells (iPSCs) from somatic cells by OCT4, SOX2, KLF4, and MYC (OSKM) transduction. However, the mechanism and upstream...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wang, Ling, Su, Yue, Huang, Chang, Yin, Yexuan, Zhu, Jiaqi, Knupp, Alec, Chu, Alexander, Tang, Young
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848184/
https://ncbi.nlm.nih.gov/pubmed/31712708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52861-8
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