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FOXH1 Is Regulated by NANOG and LIN28 for Early-stage Reprogramming

FOXH1 is a primitive-streak specifier and ACTIVIN co-effector that plays an important role in development, and positively regulates the generation of human induced pluripotent stem cells (iPSCs) from somatic cells by OCT4, SOX2, KLF4, and MYC (OSKM) transduction. However, the mechanism and upstream...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wang, Ling, Su, Yue, Huang, Chang, Yin, Yexuan, Zhu, Jiaqi, Knupp, Alec, Chu, Alexander, Tang, Young
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848184/
https://ncbi.nlm.nih.gov/pubmed/31712708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52861-8
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