Up-Regulation of P2X(4) Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain

ATP is a known mediator of inflammatory and neuropathic pain. However, the mechanisms by which specific purinergic receptors contribute to chronic pain states are still poorly characterized. Here, we demonstrate that in response to peripheral nerve injury, P2X(4) receptors (P2X(4)R) are expressed de...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Ulmann, Lauriane, Hatcher, Jon P., Hughes, Jane P., Chaumont, Séverine, Green, Paula J., Conquet, François, Buell, Gary N., Reeve, Alison J., Chessell, Iain P., Rassendren, Francois
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671487/
https://ncbi.nlm.nih.gov/pubmed/18971468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2308-08.2008
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