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Up-Regulation of P2X(4) Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain

ATP is a known mediator of inflammatory and neuropathic pain. However, the mechanisms by which specific purinergic receptors contribute to chronic pain states are still poorly characterized. Here, we demonstrate that in response to peripheral nerve injury, P2X(4) receptors (P2X(4)R) are expressed de...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Ulmann, Lauriane, Hatcher, Jon P., Hughes, Jane P., Chaumont, Séverine, Green, Paula J., Conquet, François, Buell, Gary N., Reeve, Alison J., Chessell, Iain P., Rassendren, Francois
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671487/
https://ncbi.nlm.nih.gov/pubmed/18971468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2308-08.2008
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