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The role of P2X(7) in pain and inflammation

The P2X(7) purinoceptor is unique amongst the P2X receptor family in that its activation is able to stimulate the release of mature, biologically active interleukin-1β (IL-1β), as well as a variety of other proinflammatory cytokines. Coupled with the predominate localisation of this receptor to immu...

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Detalhes bibliográficos
Main Authors: Hughes, Jane P, Hatcher, Jonathan P, Chessell, Iain P
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096758/
https://ncbi.nlm.nih.gov/pubmed/18404430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-006-9031-1
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