Up-Regulation of P2X(4) Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain

ATP is a known mediator of inflammatory and neuropathic pain. However, the mechanisms by which specific purinergic receptors contribute to chronic pain states are still poorly characterized. Here, we demonstrate that in response to peripheral nerve injury, P2X(4) receptors (P2X(4)R) are expressed de...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Ulmann, Lauriane, Hatcher, Jon P., Hughes, Jane P., Chaumont, Séverine, Green, Paula J., Conquet, François, Buell, Gary N., Reeve, Alison J., Chessell, Iain P., Rassendren, Francois
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2008
主題:
Brief Communications
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671487/
https://ncbi.nlm.nih.gov/pubmed/18971468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2308-08.2008
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