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A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation
T cell activation is mediated by signaling pathways originating from the T cell receptor (TCR). Propagation of signals downstream of the TCR involves a cascade of numerous kinases, some of which have yet to be identified. Through a screening strategy that we have previously introduced, PHA-767491, a...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6670834/ https://ncbi.nlm.nih.gov/pubmed/31402912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01718 |
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