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Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition

B7 proteins CD80 (B7-1) and CD86 (B7-2) are expressed on most antigen-presenting cells and provide critical co-stimulatory or inhibitory input to T cells via their T-cell-expressed receptors: CD28 and CTLA-4. CD28 is expressed on effector T cells and regulatory T cells (Tregs), and CD28-dependent si...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Brzostek, Joanna, Gascoigne, Nicholas R. J., Rybakin, Vasily
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740375/
https://ncbi.nlm.nih.gov/pubmed/26870040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00024
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