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CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I
Bimolecular fluorescence complementation was used to engineer CD8 molecules so that CD8αα and CD8αβ dimers can be independently visualized on the surface of a T cell during antigen recognition. Using this approach, we show that CD8αα is recruited to the immunological synapse almost as well as CD8αβ,...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245696/ https://ncbi.nlm.nih.gov/pubmed/22081144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.209 |
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