CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I

Bimolecular fluorescence complementation was used to engineer CD8 molecules so that CD8αα and CD8αβ dimers can be independently visualized on the surface of a T cell during antigen recognition. Using this approach, we show that CD8αα is recruited to the immunological synapse almost as well as CD8αβ,...

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Bibliografiske detaljer
Main Authors: Rybakin, Vasily, Clamme, Jean-Pierre, Ampudia, Jeanette, Yachi, Pia P, Gascoigne, Nicholas R J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245696/
https://ncbi.nlm.nih.gov/pubmed/22081144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.209
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