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Non-stimulatory peptides contribute to antigen induced CD8-TCR interaction at the immunological synapse

It is unclear if the interaction between CD8 and the TCR-CD3 complex is constitutive or antigen-induced. FRET microscopy between fluorescent chimeras of CD3ζ and CD8β showed that this interaction was induced by antigen recognition, within the immunological synapse. Non-stimulatory endogenous or exog...

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Detalhes bibliográficos
Main Authors: Yachi, Pia P., Ampudia, Jeanette, Gascoigne, Nicholas R.J., Zal, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352171/
https://ncbi.nlm.nih.gov/pubmed/15980863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1220
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