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Non-stimulatory peptides contribute to antigen induced CD8-TCR interaction at the immunological synapse
It is unclear if the interaction between CD8 and the TCR-CD3 complex is constitutive or antigen-induced. FRET microscopy between fluorescent chimeras of CD3ζ and CD8β showed that this interaction was induced by antigen recognition, within the immunological synapse. Non-stimulatory endogenous or exog...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1352171/ https://ncbi.nlm.nih.gov/pubmed/15980863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1220 |
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