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T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

T cells are extremely sensitive in their ability to find minute amounts of antigenic peptide in the midst of many endogenous peptides presented on an antigen-presenting cell. The role of endogenous peptides in the recognition of foreign peptide and hence in T cell activation has remained controversi...

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Bibliografski detalji
Glavni autori: Yachi, Pia P., Lotz, Carina, Ampudia, Jeanette, Gascoigne, Nicholas R.J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118480/
https://ncbi.nlm.nih.gov/pubmed/17954567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062610
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