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Initiation of TCR Phosphorylation and Signal Transduction
Recent data with CD8+ T cells show that the initial phase of T cell receptor (TCR) binding to MHC–peptide (MHCp) is quickly followed by a second, stronger, binding phase representing the binding of CD8 to the MHCp. This second phase requires signaling by a Src-family kinase such as Lck. These data p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342367/ https://ncbi.nlm.nih.gov/pubmed/22566861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2011.00072 |
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