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Fine-tuning T cell receptor signaling to control T cell development
T cell development from immature CD4(+)CD8(+) double-positive (DP) thymocytes to the mature CD4 or CD8 single-positive (SP) stage requires proper T cell receptor (TCR) signaling. The current working model of thymocyte development is that the strength of the TCR-mediated signal – from little-or-none,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119814/ https://ncbi.nlm.nih.gov/pubmed/24951034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.05.003 |
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