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Fine-tuning T cell receptor signaling to control T cell development

T cell development from immature CD4(+)CD8(+) double-positive (DP) thymocytes to the mature CD4 or CD8 single-positive (SP) stage requires proper T cell receptor (TCR) signaling. The current working model of thymocyte development is that the strength of the TCR-mediated signal – from little-or-none,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fu, Guo, Rybakin, Vasily, Brzostek, Joanna, Paster, Wolfgang, Acuto, Oreste, Gascoigne, Nicholas R.J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119814/
https://ncbi.nlm.nih.gov/pubmed/24951034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.05.003
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