Characterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular Models

Two key features of myeloma cells are the deregulation of the cell cycle and the dependency on the expression of the BCL2 family of anti-apoptotic proteins. The cell division cycle 7 (CDC7) is an essential S-phase kinase and emerging CDC7 inhibitors are effective in a variety of preclinical cancer m...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Natoni, Alessandro, Coyne, Mark R. E., Jacobsen, Alan, Rainey, Michael D., O’Brien, Gemma, Healy, Sandra, Montagnoli, Alessia, Moll, Jürgen, O’Dwyer, Michael, Santocanale, Corrado
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795371/
https://ncbi.nlm.nih.gov/pubmed/24202326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5030901
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares