Characterization of a Dual CDC7/CDK9 Inhibitor in Multiple Myeloma Cellular Models

Two key features of myeloma cells are the deregulation of the cell cycle and the dependency on the expression of the BCL2 family of anti-apoptotic proteins. The cell division cycle 7 (CDC7) is an essential S-phase kinase and emerging CDC7 inhibitors are effective in a variety of preclinical cancer m...

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Detaylı Bibliyografya
Asıl Yazarlar: Natoni, Alessandro, Coyne, Mark R. E., Jacobsen, Alan, Rainey, Michael D., O’Brien, Gemma, Healy, Sandra, Montagnoli, Alessia, Moll, Jürgen, O’Dwyer, Michael, Santocanale, Corrado
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795371/
https://ncbi.nlm.nih.gov/pubmed/24202326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5030901
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