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Targeted Approaches to Inhibit Sialylation of Multiple Myeloma in the Bone Marrow Microenvironment

Aberrant glycosylation modulates different aspects of tumor biology, and it has long been recognized as a hallmark of cancer. Among the different forms of glycosylation, sialylation, the addition of sialic acid to underlying oligosaccharides, is often dysregulated in cancer. Increased expression of...

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Detalhes bibliográficos
Main Authors: Alessandro Natoni, Raghvendra Bohara, Abhay Pandit, Michael O'Dwyer
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
Colecção:Frontiers in Bioengineering and Biotechnology
Assuntos:
Acesso em linha:https://www.frontiersin.org/article/10.3389/fbioe.2019.00252/full
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