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Lack of Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease after Overexpression of the Anti-Apoptotic Protein Bcl-2
Alzheimer's disease (AD) is characterized by the accumulation of plaques containing β-amyloid (Aβ) and neurofibrillary tangles (NFTs) consisting of modified tau. Although Aβ deposition is thought to precede the formation of NFTs in AD, the molecular steps connecting these two pathologies is not...
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| Publicado no: | J Neurosci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6670712/ https://ncbi.nlm.nih.gov/pubmed/18354008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5620-07.2008 |
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